So stays designed for 2.3"s on a 73mm shell will need to angle in more to fit a 100mm shell, but wouldn't have the space for 4.0" even at the design angles.
Fatbike would be 100mm or 120mm BSA shell, with OLD of 170 or 190mm for QR, 177 or 197 for thruaxle. The wider spec tends to be for ~5" tyres, but there are plenty of frames which use the 190 rear with a 100mm BB.
135mm rear +35mm = 170mm
73mm +35mm = 108mm
2.3 * 25.4 = 58mm, 58+ 35mm = 93mm
So stays designed for 2.3"s on a 73mm shell will need to angle in more to fit a 100mm shell, but wouldn't have the space for 4.0" even at the design angles.