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What/How/When are you using it?
I used it to take the Brompton on an EasyJet flight to Turkey. Not long back.
I used the bag as my sole hold luggage, with my clothes around it for padding. Worked fine, no damage to the bike at all. I could, at the far end, have put my clothes into the Brompton-luggage-carrier-compatible bag I used as a cabin bag and cycled off, but my partner doesn't pack light and had her bike in a bomb-proof case, so I didn't.
Because the bag has no wheels, it'd be a struggle to carry the fully packed travel bag any significant distance if you're not in good shape. I just put the detachable straps in an arrangement that let me carry it on my back.
Worked for me, will use again.
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Apparently if you have a rack on your Brompton, you can "fold" up the Vincita travel bag and bungie it to the rack.
https://www.flickr.com/photos/itsbruce/sets/72157689467939225/with/36594049903/
Found a travel bag that comes in a backpack, so that you can arrive, unpack the bike and ride away with the travel bag on your back or hanging from the handlebars. Not a lot of room in the backpack for anything else (but some), so you either travel light or have another bag. There's light padding in the walls of the bag but If you were taking it on a plane you'd want to add some bubblewrap and put clothes around it - it's a slightly roomy fit for most folded bikes so there's space for clothes. I'm going to be trying just that in a few days, so I'll report back.
Given the dimensions of the travel bag (34 * 68 * 85 cm), you could fit some models of medium-sized road bikes in it if you disassembled them and still have room for some clothes.
Isn't perfect but it's a flexible solution, cheap as these things go (£58 on Amazon Prime but as little as £34 from some UK eBay shops).