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onyerbike-
You'll have to weigh up pros and cons of both then. I have no experience in this field.
@umop3pisdn can maybe advise?
You've got weight saving on the narrower ones. Aero benefits if you're going to use narrow tyres.
Compared to better tyre profile, lower rolling resistance, better cornering grip/stability, more aero with wider tyres on the wider rims
PhilDAS
Are you hillclimbing or longer distance road riding with flat and/or descents?