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I'd say that there is. Mobil 1 is a top-end fully-synethetic oil. Castrol GTX is a run-of-the-mill semi-synthetic - i.e. not really synthetic at all, just boggo mineral oil with an extra helping of additives. It'd be like topping up your Chateau Mouton Rothschild 1982 with a touch of Casillero del Diablo Merlot.
Any reason to avoid topping up an engine full of 10w40 Mobil one with 10w40 Castrol GTX?