-
I'm not sure ACA has a huge impact either way.
People who can't afford insurance (especially those with pre-existing conditions) will cut corners on preventative care and "maintenance" meds. Treating an acute condition costs a lot in terms of bed occupancy and staff, but the profits available on the actual medication will be less than for preventative.
If the US centralise purchasing
That's gonna take a massive shift. The time to do that in the US would have been 50-60 years ago, when even the Republican party had a lot more social conscience than today's Democrats.
The long game for Merck is for health insurance to keep funding their products. Millions of people being priced out of healthcare by killing or crippling ACA isn't going to move more product.