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What exactly are you running? SRAM 36T with medium cage Di2? Are you using Wolftooth?
I might try one of these 34T Shimano cassettes or see what the go is with running 11spd Shimano MTB hubs and cassettes on road.
https://www.cxmagazine.com/shimano-xtr-m9000-11-speed-road-compatible-questions
Can I use the XTR M9000 cassette on my 11-speed road setup?
Maybe. It should clear your spokes and fit on your 10-speed and 11-speed (with a spacer) freehubs, but your rear derailleur will likely be incompatible with the 40t cog. However, some clever folks have figured out that a longer rear derailleur B-screw can be a cheap hack to make it work.
Also: http://forums.mtbr.com/cyclocross/xtr-11-speed-40t-cassette-11-speed-road-shifters-945660.html
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What exactly are you running? SRAM 36T with medium cage Di2? Are you using Wolftooth?
Ultegra med cage with SRAM 1130 11-36: https://www.pedalroom.com/bike/carbonda-gravel-bike-1x11-di2-30292#photo239239
No wolftooth, B screw is about 70% in so if there was a 38t it would also work.
Can I use the XTR M9000 cassette on my 11-speed road setup?
I don't think so unless you go for an XT (or XTR Di2) rear mech. Maybe @Emyr can clarify.
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11spd Shimano MTB hubs
...are the same as 10spd Shimano MTB hubs. 11sp MTB cassettes overhang the base of the freehub.
XTR M9000 11-40 11sp cassette (from eBay, lightly used) on XT M8000 hub, Ultegra 6870GS 11sp medium cage mech. No fancy mech hanger, but Surly Straggler frame, so mech hanger is probably longer than normal road hangers.
Haven't touched the b-screw at all, it's at whatever it was set in the factory.
I am using 36t comfortably with med cage, wanna buy my rear mech? I do you good deal.