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Jon.
Yes, I set up a pair of CX50 on my girlfriend's old Van Tuyl cross bike. You can see them on it here https://www.lfgss.com/conversations/295582/#comment13331050
They have long washers on the brake bolts, so remove those and fit smaller ones and they are a wider spread apart than regular cantis
I'm sure it's not technically recommended, but it does work in my experience