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I suspect it was something to with the preparation of the steel, ( more/better required for water based paints),
and possibly something to do with the difference between the climatic conditions of South Africa, (generally warmer/less humid?), compared to the UK, (cooler /routinely damp almost perfect for the rapid onset of rust).I'm guessing that each successive model of E-Class uses thinner steel to reduce weight?
Daimler owned Chrysler for a while, hence the 300C, (based upon the outgoing E-series platform), and the Crossfire, (based upon previous SL?).
It was claimed on the vegetableoildiesel forum that 'R'/'S' reg E-class suffered from the first generation of MB water based paints,
with poor edge effects hence ubiquitous rusty boot edges and boot lock holes.
Add in the UK rhd models were, so I read, assembled in South Africa, these are the ones to avoid, unless the spec or service history convinces you to budget for respraying the troublesome areas.