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uphilldowndale
Serling
27"=630mm wheel diameter minus 650B=584mm gives you 46mm, divided by 2=23mm. So check the drop on the current calipers you've got (if any) for 27" wheels and add 23mm. I reckon the drop would be too much.
You would be better off with a frame built for 700c or the old 26 X 1 1/4 for a conversion.