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You want to be doing exercises which target muscle groups which help with stability, especially with the knee.
Hypocrite alert though as I have been neglecting this and now have a fucked knee after trying to do a 60mile+ week...
Squats, lunges and things like this:
http://www.njsportsmed.com/files/myrtl_routine.pdf -
I think there's an argument for deliberately exercising muscles that running doesn't develop, in order to avoid an imbalance. I used to have knee pain - specifically patellar tendonitis - and I believe it can be caused by the quad having to work too hard, since your hamstring strengthens more through running than the quad does. The best exercise suggested for this was one-legged squats, particularly on an incline board to help isolate the effort in the quad rather than the lower leg.
I don't think you're in danger of building up the quad too much, especially in terms of bulk, if the majority of your exercise is aerobic.
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pifko
PhilPub
@Brum
Been having shooting pains in my left knee only when descending. The first ultimate fear is cartilage, but I have seen that doing quad strengthening exercises to build quad muscles can help, but is it not better to stay away from building muscle as a runner, and using only the muscle you need to run, and not excess?