Wheels, there isn't too much between a £200 set and a £400 set. You need to get in to £500+ to get much better ones. So I would go for something like this http://www.wiggle.co.uk/fulcrum-racing-7-lg-alloy-clincher-wheelset/ + Some quick but tough tyres like http://www.chainreactioncycles.com/michelin-pro4-endurance-v2-black-25c-free-tube/rp-prod145962
@Sumo started
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Wheels, there isn't too much between a £200 set and a £400 set. You need to get in to £500+ to get much better ones. So I would go for something like this
http://www.wiggle.co.uk/fulcrum-racing-7-lg-alloy-clincher-wheelset/
+
Some quick but tough tyres like
http://www.chainreactioncycles.com/michelin-pro4-endurance-v2-black-25c-free-tube/rp-prod145962