Quick wheel change on something like the Open UP from 700 road to something 650b gravel-ish might work...
These two did it on 43mm tyres... http://www.bikepacking.com/plog/trans-america-off-road-trail-odyssey/
Another bike? umadbro?
Nah, I think a fast TransAm is enough of a goal for me.
@hippy started
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Quick wheel change on something like the Open UP from 700 road to something 650b gravel-ish might work...
These two did it on 43mm tyres... http://www.bikepacking.com/plog/trans-america-off-road-trail-odyssey/