If you were considering the open up, have a look at a santa cruz stigmata. Much dollar but very nice.
Not sure the Stigmata will take up to 650b/2.1
Are there any OTP frames/bikes (other than the Open UP) that take a 650b/2.1 wheel?
A fair few surlys, salsas and somas do Im sure
Mason Bokeh & Bowman Foots Cray.
@Dan_W started
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If you were considering the open up, have a look at a santa cruz stigmata. Much dollar but very nice.