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@fredtc
No, I don't think so - from
http://cyclingtips.com/2014/10/mixing-groupsets-what-works-together-and-what-doesnt/
"As the brains behind the operation, each brand’s shifters must be matched with their own derailleurs, especially the rear derailleur, in order for the indexed system to function properly. As noted above, there is little or no backwards or forwards compatibility for Shimano, Campagnolo, or SRAM. It is possible to cheat with the front derailleur since there is more tolerance for variation in shifting but as the least expensive component in a groupset, there is little to be gained by leaving it out when upgrading your transmission."
But if you have a narrow wide chainring, with a road derailleur, so long as your chain is the correct length I'm pretty sure you won't experience any chain drop. I rode with that set up all last season and had no problems. You will just get more chain slap than with a clutched RD. If you want to be super safe then you could fit a chain guide (eg a gussett lil chap) but IMO it's not necessary.