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Experiment with flavours and record your mixes so you remember what you like and don't.
leave caramel/Vanilla and other rich flavours to steep for a week or so for better taste
Use high qual flavours
Shake well, and shake well again (and again)
Keep equipment sterile
Use a mix calculator and measure accurately esp the Nicotine (http://www.steam-engine.org/juice.asp)
Taste the liquid. It should taste good.
Anything to look out for when making your own liquids? hints, tips, caveats, do's, don't's?