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Clicking on:
in reply to
takes you to the comment in the context of the thread in which it appears, which may be on the same page but higher up, or may be an earlier page in the thread.#number
in the top right of a comment, takes you to a permalink to the comment as a standalone thing, and if the comment was in reply to another then it will show the parent there, and if other comments were in reply to it then those appear below the comment.
Use the first to see how it appeared in the grand scheme of things.
Use the latter to have a permanent record of "this was in reply to that, and had all these responses too".
i.e. this is the numbered link to your comment: https://www.lfgss.com/comments/13057597/ and you can see it with all of it's interactions around it.
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The arbitrary bit seems to be what comes up when you click on a comment number. For instance clicking on the second comment in a three comment thread gives you all 3 comments as expected https://www.lfgss.com/comments/13057398/
Clicking on the third comment only gives you the 2nd and 3rd comment https://www.lfgss.com/comments/13057404/
Clicking on the comment number of the reply should take you to a single comment (or sometimes a thread of comments, it seems a bit arbitrary) which was the original post.