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Very late to this but apart from the obvious that @andyp pointed out (all the athletes being caught doping with it) the point with meldonium/Mildronate is OK, even if Sharapova has a heart problem, why was she taking it?
It's an old drug sold in just a few Eastern European countries that also just happens to boost exercise tolerance. The scientific evidence for Mildronate is limited compared with medicines widely available in Europe and the U.S. (where she trains), which also have full regulatory backing and years of robust safety/efficacy data.
It's also not licenced by the FDA in the U.S. or the EU. So why risk it?
Fox
While I don't condone sharapova I do wonder why a drug created for heart problems was completely banned. Melodinium is meant to taken in 4-6week batches, a maximum of 3 times a year. If pros are still allowed to take steroids for colds with a TUE, then why can't athletes diagnosed with a heart problem be allowed to have CONTROLLED (in caps so you all don't get excited) access to this?