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I’ll have to measure but I suspect the Big Apple Plus will be just too dang big. At least the 50-406 Big Apples come with the Raceguard level of puncture protection.
I can get great puncture protection at 47 with the Marathon Plus and with the Big Apple plus in the 55. There are just no bulletproof tyres in a 50 though. Conti don't seem to make anything. Do Panasonic make anything that size? I have Ribmos on the commuter bike and the last set I replaced looked like an experiment with shrapnel - but zero punctures in 18 months.
If you are running internal gears and a dynamo, then puncture protection is a definite +
You can get the Big Apple Plus in a 55; not sure if they'd fit, but it would look and ride amazing and it's give extra puncture protection over the regular Big Apples.
Last year I ran 23C 451 on my Kingpin and this year I bumped them up to a spongy 28, so I can only imagine what 45+ would feel like.
Your post is perfect timing, 'cause I rode it this morning for the first time since last summer and I'd forgotten how much fun it is!
Thanks for sharing the @brokenbetty thread as well, that was a good read.