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@bertocq
Giant Defy Advanced Pro 1 £3,249.00
Giant Defy Advanced SL 0 £5,499.00
Ok Giant uses 140mm rotors.. dunno if 160mm would fit... need some research or just walking in a Giant shop up there.
The Cube Agree range have many versions but none with Di2 (although frame seems compatible...)
Edit: Ok sorry, was slow writting, I'll look some more before answering again