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The only swap out I've made is the mechanical pull calipers, disc wheels and rotors, and the frame obviously. Actually relatively painless.
Build list looks something like:BlackInc Frame
Cx77 Cable Pull Calipers
Ultegra ST-6800 shifters
Ultegra RD - 6800 rear mech
Ultegra FD - 6800 front mech
Ritchey Superlogic stem, bars, post
Ashima rotors (lightest I could find at 66g)
Selle Italia SLR Ti saddle
Look keo blade Ti pedals
Wheelset is CKR45 x DTSwiss440 (Aksium disc as placeholder/commute)Can't think of anything else....
Will probably need post mount 140-> 160mm calipers adapters as I'm going to run 160mm front and rear.
got a build list for your caad disc? can you run rim brakes on a caad disc frame? tempted at that price but dunno much about discs so wouldn't know where to start with a build