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+1 Runners Need, Canary Wharf. If the same guy's in charge he's a keen runner and distinctly non-salesman-like, in a good way. They also have a good price-match policy against online goods.
I think the jury's still out on the value of "gait analysis" by treadmill/video, but short of having a proper biomechanical assessment with an expert, at least it gives you a chance to try on a number of shoes from different manufacturers whilst actually running. Go for the ones that fit best and feel most comfortable.
Avoid Sweatshop, and their sales staff who are incentivised (I believe) to try and sell you Karrimor shoes and/or expensive insoles.
Best place central or east for a gait analysis and some new sneaks?