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Depends on the brand of course but let's take The Flat Head as an example (14oz, raw as standard most of the time).
Before you've even put them on it takes 2 washes to get the shrinkage out of the cotton. The build quality and dyeing process is so good that you loose virtually no colour from a 40 degree wash, no spin.
I stick to a hand wash, reasonably warm, non bio and a hang dry. Cotton and denim needs a tremendous amount of water to grow well. A wash to clean and rejuvenate goes a long way.
Hilarious chat on not washing denim.
Just visit Japan and chat to any of the bods / shops where you can pick up some of the best quality denim found anywhere in the world and even intimate you don't wash your jeans and they'll look at you like you're insane.
In the long run it damages the denim more quickly, fact. Washing doesn't have to be in a machine at 30-40. Anyhow, not the time or place.
Go ahead and take pics of your unwashed denim. Rad!