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I used Biopace on my geared bike for years and always seemed to get on with it. When my commute distance went up and was pan flat I switched to doing most of my miles with fixed gear. At that point, the Biopace started to feel a bit strange, sort of inefficient feeling in getting the power through to the wheels. I think it's because the gearing gets taller in the dead spots, which means the feet slow down somewhat. I wonder, in hindsight, if this sudden change in velocity at the top and bottom of the stroke was a contributing factor in my knee injury. I've currently got round rings on the geared bike and I have to say they go round more smoothly than the Biopace did.
Tldr; I haven't made my mind up yet about Biopace :D
Jonny69
@lynx
I like biopace rings and have them on a couple of bikes.