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Shimano Claris 11-28 have a slightly better jump than the SRAM 11-28, see below*.
Get the Spa Cycles for one reason - the square taper mean you can try and get the shortest bottom bracket possible for the low Q-factor, I managed 107mm with the double crankset with a couple millimeters of clearance on the arm despite recommendation of 113mm, the fact it's 165mm mean there's a little more clearance with the chainstay and thus might be able to push it down to 103mm.
The Hollowtech one as great as they are, have one fixed q-factor.
*Claris; 11-13-15-17-19-21-24-28
SRAM; 11-12-14-16-18-21-24-28
Thanks both.
Her usage is commuting and occasional mini touring; she is currently using SS so 1x8/9/10 would be plenty for her.
Will this setup work?
Shifter: http://www.chainreactioncycles.com/shimano-tiagra-r400-8-speed-down-tube-shifter/rp-prod13671
Cranks: http://www.spacycles.co.uk/products.php?plid=m2b0s109p1698
Another option for cranks: http://www.evanscycles.com/products/shimano/fc-3550-sora-9-speed-compact-chainset-ec041355
RD: http://www.evanscycles.com/products/shimano/altus-m310-mega-range-7-8-speed-rear-derailleur-ec070096
Cassette: http://www.wiggle.co.uk/sram-pg850-8-speed-cassette/
Chain: http://www.rosebikes.co.uk/article/sram-pc-870-chain/aid:249793
Any advantage to direct mount MTB rear derailleurs? The frame hasn't been built yet so can opt for PMW rocker option for those.
Can you get 104bcd in road Q factor? That and 165mm crank length is essential for her fit.
Next question disc wheels; not too boat anchor but not crazy expensive.