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@bothwell
I have a Bontrager Affinity RL on my road bike, which has a dip rather than a full cut-out, and it's served me well over many miles: http://www.bontrager.com/model/08799
I have heard tell that ISM Adamo saddles (the ones with the forked noses, they don't do women's versions) are well-regarded by female athletes in the comfort stakes, but at 100+ squids, she'd need to give it a bloody good test before buying. And it'd completely change her position. Though it sounds like she's needing to change her position now anyway.
Any and all of the recommendations we give might well end up being complete garbage for her, unfortunately. It might be easier to get a selection of saddles from literally everyone you know and have Liz test them all out, as this can be a bit of a dark art :/