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Businesses fail (or just close) all the time. Most new businesses fail. If the closure of one example business means the basic concept doesn't work, restaurants are clearly a bad idea doomed to extinction.
I'd imagine that Sigma or Mosquito have more in common with Bike Room that that lot, and I know at least Velorution isn't exactly a poster-boy for economic viability :)
The examples I cited are more leisure bikes than hardcore roadie but still, overpriced and aiming at the well-heeled. As for Velorution's busines model, it can take several years to turn a viable business into a profitable one. Smart money knows that.
I'd have said the same about a shop selling cycling clothes in the West End but Rapha seem to be doing quite well.