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Thank you all very much for your help.
As hippy says, I get round in relative comfort but just get slower and slower as the ride goes on (who'd a thunk it?). I suppose that one of my worries is that one of the ways that I deal with getting through an audax is to try and keep it to a reasonable length of time, and that was possible with a 300, but probably isn't with the 400.
To that end I am actually more concerned about the 400 than the 600. My 300 took me 13 hours all told, which means that I am thinking in my head that the 600 is basically two 300s separated with 6 hours sleep, which I think is probably plenty (or does it not work like that in practice)
Anyway, thank you all for your help.
"Specificity may help if you're goal is to do stuff fast, but it's not required if you just want to get round"
But he already gets around, his goal is to do it faster.