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Are you pushing/going very quickly? Intrigued by this, I've done up to 6 days of 100+ miles per day and never noticed any loss of appetite. Doing a circuitous 9-10 day LEJOG this year which will be comfortably 100+ a day and the eating was one of the things I was most looking forward to. And the beer, obviously. Got to wash it all down with something... hope I don't suffer this.
I have never found this. Maybe I haven't ridden as far or for as long as you are relating to, but when I've done 3,4 or 5 day rides of 100+ miles a day eating remains an absolute pleasure and each excessive (but justified because fueling) meal becomes a highlight. And pudding. Lots of pudding.