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Have you got any suggestions for hackney wick to charlton? Ideally I'd use the A12 but my current route is this:
https://www.google.co.uk/maps/dir/80+Eastway,+London+E9+5JH,+UK/51.4892871,0.0302814/@51.5072585,-0.0127688,14z/data=!4m29!4m28!1m25!1m1!1s0x48761d0dfd68750b:0x6ccf421c64fd01d5!2m2!1d-0.0293215!2d51.5471197!3m4!1m2!1d-0.0354103!2d51.5404698!3s0x48761d19f168e6ff:0xc29dae0a0885cb3e!3m4!1m2!1d-0.0280073!2d51.5121652!3s0x487602cb993df69b:0xe0a41402dfff780e!3m4!1m2!1d-0.0272024!2d51.5068169!3s0x487602c8e4a50415:0x62a2c5424542c71c!3m4!1m2!1d-0.0270015!2d51.506332!3s0x487602c8f00a29b1:0x65d07cbd0d54bb7c!1m0!3e1Which includes some hideous junctions (notably around westferry) and is clearly not very direct!
I'd prefer to avoid narrow/canal paths if possible...
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You've picked a pretty impermeable stretch of London to traverse. :)
I'd probably go from Hackney Wick to Fish Island, cross the A12 at Old Ford Road (cycling and walking bridge), do Parnell Road, Fairfield Road (both fairly busy), then Campbell Road, Violet Road (various dog-legs), Morris Road, Chrisp Street, cross the A13 into Newby Place, and go east along Poplar High Street.
Unfortunately, if you get to the island on that side, there's no way of avoiding the big roundabout (Aspen Way/Cotton Street/Trafalgar Road/Preston's Road) unless you want to do the Blackwall Tunnel. It has been done, but for a regular commute you might well be ever so slightly too predictable. :)
Anyway, then Preston's Road, Manchester Road, East Ferry Road from the small roundabout (filtered in the middle), through the tunnel, etc.
It's worth trying, although in Tower Hamlets most of these fairly minor streets tend to carry high-ish volumes of through motor traffic because there's basically no attention been paid to strategic traffic management. And unless you want to go out of your way, the big roundabout is a given, unfortunately.
There have to be more (non-motorway) river crossings in that stretch--obviously, TfL's hideous Silvertown Tunnel proposal is not the answer.
Forgot: You can also get onto a short stretch of the Thames Path from Narrow Street and avoid Westferry Road and Westferry Circus. You can then get off the Thames Path at Sir John McDougall Gardens and take Tiller Road to Pepper Street.