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Got this thought as well for my Croix de Fer. Got a 36/46 on the front and 12-32 on the back (ostensibly 11 speed but free hub is too narrow so dropped the 11 speed cog). For the riding I've done so far I haven't been out of the 36, but I think when I put some slicks on and take it on the road I'll use the 46. The thought of 1x10/11 scares me unless you're doing one type of riding only.
Have said that, people tour on fixed so...
@edscoble Am I totally bonkers thinking about doing a 1x10 setup on a gravel grinder / light tourer? I was thinking going 44t Narrow Wide in the front and a M771 11-36 mtb cassette in the back. Advise please.