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A higher pressure tyres give you a much smaller contact point, so all (hypothetically) 100kg of you and the bicycle are in this tiny contact point that does not provide much "give" at 100psi.
The main reason why people ride at this pressure, is because it feel faster.
This mean that when you run over a debris, it have a much higher chance of getting embedded.
A lower pressure tyres provided not only provide a wider contact point for all 100kg of you, but it have a lots more give to prevent the debris from getting embedded in the first place, providing that you drop the pressure accordingly.
Think of how jarring it is to hit a pothole with 23mm and 120psi, compare to a bigger tyres with a lower pressure.
Grand Bois work best under a much lower pressure, the less pressure it have, the less likely it'll get puncture.
The girlfriend's bike have the 650b Grand Bois 32mm tyres, and she ran them at around 60 in the back and 45 in the front (she's tiny), her commute take her to Old Street from Oval, so far no punctures.
Which model was it again? 32mm?