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If you're saying the frame is (pretty much) last on the list of changes you can easily make. I agree.
I just wanted to add that Fred Average benefits from aero gains more than a powerful rider. The buying public still haven't completely got their heads round this I think, but eventually they will.
I disagree about 'losing by a wheel' being the only time gains make sense. Sometimes aims are more humble, but the margins are the same.
Engineers will keep making aero frames and the weight and comfort penalties of those frames will vanish and we'll all go 0.16kph faster :)
Yes, you're being disingenuous though - the point I'm making is that those gains are easy to find in so many other areas that it's not worth looking for them in a frame at the expense of handling and comfort. Fine - if your position is dialed, stem slammed, you have Zipps, skin tight clothing that fits properly, an aero-optimised helmet, shaved legs etc etc etc then sure, go look for the 5-10w saving in a frame. But otherwise it's like advocating the use of a disc wheel for sportive riders.