This was 210-ish miles on 28c Randonneurs at 100psi. I had spasms in my hands, particularly thumbs for a few days afterwards but I think much of that was down to my bar/hoods setup being slightly off.
Couldn't really fault the bike itself, even outside of its normal working conditions.
At about the hundred mile mark on my Gangsta, during an aforementioned 200+ mile jaunt in July.