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@Ordinata
My 2 Mamil pence.
Carbon frame if you can afford it. A much better medium to soak up the predominantley alloy components.
Carbon wheels are great, again if you can afford to replace once brake track is shot. Alloy track much more durable.
I have been getting lower back pain on road bike. I noticed if I alter my posture to a more open position (straighter back) it improves immediately.
Don't get on TT bike at all tho. (Aluminium) /End