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@ewanmac
I'm in Flagstaff so c.2,100m according to wikipedia. The highest I'm likely to get is a ride up to the Snowbowl ski resort which I think is about 2,800m.
There is nothing very scientific about it but I'm just fascinated to observe how my body responds to the different environment. Z2 felt completely normal except that my HR was way higher than I'd expect at sea level. Z3 was perhaps a bit more laborious than normal but I still felt like I could have stayed there for ages. If I pushed any harder than that things fell apart rapidly... I was supposed to do a series of 2min efforts in Z6 and I could hit the numbers easily for the first few seconds but by about 30secs I was really struggling. If I dropped the intensity back to Z5 I could keep hold for about 90secs before the same dying. It never hurt but I just felt completely empty and started getting a headache towards the end.
Fascinating.